Liporase
Liporase (hyaluronidase) is a vial that can be used to dissolve hyaluronic acid (HA)-based dermal fillers that have been placed incorrectly, excessively, or unevenly. Liporase can also be used in emergency situations where dermal filler has been injected into an artery, causing the occlusion of one’s blood supply.
Storage of Configuration Fluid:​
1. Liporase (Liporase injection) Ovine is supplied sterile as 200 USP Units/ mL of ovine Liporase non-preserved, 1.2 ml in a single-use 2 mL glass vial with a rubber stopper and aluminum seal.
2.Protect from light.
3.Store unopened vial in refrigerator at 2° to 8°C (35° to 46°F).
4.Do not freeze.
5.Storage of Configuration Liquid: The formulated lysozyme is extremely unstable in aqueous solution and should be prepared before use. The remaining solution can be stored at temperatures below 30 degrees for 2 weeks, but if it is discolored or precipitated, it cannot be reused.
Note: Perform a patch test to ensure that no allergic reaction will occur. Inject Liporase Hyaluronidase subcutaneously and wait 20 minutes to assess any allergic reactions.Redness and slight swelling after the injection are normal.Do not proceed with treatment with Liporase in the cse of hives or other signs of allergy.When dissolving dermal fillers .
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1. Add 1.5ml of saline to the Liporase Hyaluronidase ampoule.
2. Gently and slowly twirl the ampoule to mix, being careful to not shake too hard.
3. Draw out the mixture with a syringe and slowly and carefully inject it into the area where the filler needs to be dissolved.
4. The Hyaluronic Acid filler will start to dissolve right away and will be naturally absorbed by the body.
5. Check the area for traces of the filler after 1 week. If any traces persist, repeat the procedure.
When boosting fat dissolving injections:​
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Mix 5cc of saline with 1 vial of Liporase Hyaluronidase.
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Inject the Liporase solution into the area where the fat dissolving injections will be administered.
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After finishing the Liporase injections, administer the fat dissolving injection according to the product instructions. Tip: It is best to administer the Liporase and fat-dissolving injections separately, rather than mixing them in the same syringe.
To remove filler, Liporase should be injected into the skin to dissolve the HA acid found within dermal fillers. To increase the effects of the injection, Liporase can be added to a fat melting injection. It can also be combined with a local anesthetic. To use Liporase, first mix 3cc of saline into 1 vial of Hyaluronidase. This will dissolve 3cc of hyaluronic acid. Liporase should be injected, along with lidocaine for numbing relief, into the area where the filler needs to be dissolved.
Hyaluronic acid filler will start dissolving immediately and will be entirely absorbed by the body within a few hours. Massage the treatment area for 15 minutes daily for the length of one week. Apply a warm compress to the treatment area after the massage. Please note that there have been a few reports that some people may have an allergy to hyaluronidase, which happens to those who are allergic to bee stings.